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MSM Powder 99.9% Bulk Supplier for Supplements & Cosmetics
Methyl Sulfonyl Methane (MSM, CAS No.: 67-71-0) is a naturally occurring organic sulfur compound with the chemical formula (CH₃)₂SO₂. Our mesh includes 20-40mesh, 40-80mesh, 60-100mesh. Our premium MSM Powder boasts a minimum purity of 99.9%, produced via an advanced multi-stage distillation process that eliminates contaminants and ensures exceptional consistency. It is an odorless, tasteless, and stable crystalline powder that is naturally present in human tissues, plants, and food sources.
As a rich source of bioavailable sulfur, it plays a key role in the synthesis of structural proteins such as collagen and keratin. Free from GMOs, gluten, allergens, and synthetic additives, this product meets the stringent requirements of B2B applications in nutraceuticals, pharmaceuticals, and cosmetics, aligning with global regulatory standards, including EU Regulation (EC) No. 1161/2011 and FDA.

Key Features
Ultra-High Purity: 99.9% minimum purity, verified by third-party testing, ensuring minimal impurities and optimal performance in formulations .
Excellent Solubility: Fully dissolves in water and polar solvents, enabling easy integration into powders, capsules, tablets, and liquid supplements.
GRAS & Regulatory Compliance: Classified as GRAS (Generally Recognized As Safe) by the FDA and approved for use in dietary supplements across the EU, USA, and Canada.
Stable & Free-Flowing: Maintains stability under recommended storage conditions; free-flowing texture prevents clumping, facilitating automated production processes.
Clean Label Profile: Non-GMO, gluten-free, allergen-free, vegan-friendly, and certified Kosher & Halal, meeting diverse market and consumer demands.
Low Heavy Metal Residues: Strict quality control ensures lead, arsenic, and other heavy metals are below international safety limits (≤0.1 mg/kg).
Functional Benefits
Supports Structural Protein Synthesis
Provides bioavailable sulfur, a key building block for collagen and keratin, supporting the integrity of connective tissues, skin, hair, and nails.
Promotes Product Stability
Chemically stable, does not degrade in formulations, extending the shelf-life of finished products.
Neutral Organoleptic Profile: Odorless and tasteless, does not alter the flavor or aroma of capsules, tablets, or topical products.

Enhances Formulation Versatility
Compatible with vitamins, minerals, amino acids, and herbal extracts, ideal for multi-ingredient supplement blends (e.g., with glucosamine or chondroitin).
Supports Skin & Hair Health
Suitable for topical formulations, helping maintain skin hydration and hair strength when incorporated into cosmetics and personal care products.
MSM Powder Applications by Industry
Methyl Sulfonyl Methane Powder (MSM 99.9%) is widely used across nutraceutical, functional food, cosmetic, and pharmaceutical industries due to its excellent solubility, high purity, and neutral sensory profile. Its bioavailable sulfur content makes it particularly suitable for joint health, beauty-from-within, and anti-inflammatory formulations.
MSM for Joint Health Supplements
MSM is one of the most commonly used ingredients in joint support formulations. It provides bioavailable sulfur required for the synthesis of collagen, glucosamine, and connective tissues.
Typical applications include:
- Joint support capsules and tablets
- MSM + Glucosamine + Chondroitin formulas
- Bone & cartilage health supplements
- Sports recovery formulations
- Mobility support powders
- Senior joint health nutraceuticals
Formulation advantages:
- Neutral taste suitable for capsules and tablets
- Excellent compatibility with glucosamine & collagen
- High purity reduces formulation instability
- Suitable for high-dosage products

MSM for Functional Beverages
Due to its water solubility and low odor, MSM powder is increasingly used in functional drinks and ready-to-mix beverage formulations.
Common beverage applications:
- Joint health drink powders
- Beauty-from-within beverages
- Collagen + MSM drink blends
- Sports recovery drinks
- Anti-inflammatory functional beverages
- Effervescent tablets
Technical advantages:
- Fully water-soluble
- No sedimentation
- Neutral taste profile
- Stable under beverage pH conditions
- Compatible with vitamins and minerals
MSM for Capsules & Tablets
MSM powder is widely used in solid dosage forms due to its free-flowing properties and stability.
Typical dosage formats:
- Hard capsules
- Tablets
- Effervescent tablets
- Sachet powders
- Stick packs
- Soft gel blends
Manufacturing benefits:
- Good compressibility
- Uniform particle size
- Low moisture content
- Excellent blending performance
- Suitable for high-load formulations
MSM for Cosmetics & Personal Care
MSM is also used in cosmetic and personal care formulations due to its role in supporting keratin and collagen production.
Typical cosmetic applications:
- Anti-aging creams
- Skin repair serums
- Hair growth shampoos
- Nail strengthening treatments
- Anti-inflammatory skincare
- Acne treatment formulations
Functional advantages:
- Sulfur source for keratin production
- Supports skin elasticity
- Improves hair strength
- Suitable for topical formulations
- Compatible with botanical extracts

Technical Specifications & Analysis
|
Physicochemical Index |
Standard |
Test Method |
|
Purity (MSM Content) |
≥99.9% |
HPLC |
|
Particle Size |
40-80 Mesh (Customizable) |
Sieve Analysis |
|
Moisture |
≤0.5% |
Karl Fischer Method |
|
Ash |
≤0.1% |
Gravimetric Method |
|
pH Value (5% Solution) |
5.5-7.5 |
pH Meter |
|
Melting Point |
109-112℃ |
Differential Scanning Calorimetry |
|
Bulk Density |
0.8-1.0 g/cm³ |
Bulk Density Tester |
|
Heavy Metals (Pb) |
≤0.1 mg/kg |
ICP-MS |
|
Arsenic (As) |
≤0.1 mg/kg |
ICP-MS |
|
Cadmium (Cd) |
≤0.05 mg/kg |
ICP-MS |
|
Mercury (Hg) |
≤0.01 mg/kg |
ICP-MS |
|
Microbiological Index |
Standard |
Test Method |
|
Total Plate Count |
≤10³ CFU/g |
ISO 4833-1 |
|
Coliform |
≤10 CFU/g |
ISO 4832 |
|
Mold & Yeast |
≤10 CFU/g |
ISO 21527-1 |
|
Salmonella |
Negative/25g |
ISO 6579-1 |
|
E. coli |
Negative/g |
ISO 16649-2 |
|
Staphylococcus aureus |
Negative/g |
ISO 6888-1 |
MSM vs Glucosamine
MSM and glucosamine are commonly used together in joint health supplements, but serve different functions.
MSM provides bioavailable sulfur, which supports collagen synthesis and connective tissue integrity. It also contributes to anti-inflammatory support. Glucosamine primarily supports cartilage structure and joint lubrication.
Key differences:
| MSM | Glucosamine |
|
Sulfur donor Anti-inflammatory support Collagen synthesis support Suitable for beauty supplements |
Cartilage building block Joint lubrication Structural joint support Typically used in higher doses |
Best practice:
MSM is often combined with glucosamine and chondroitin to create comprehensive joint support formulations.
MSM vs Collagen
MSM and collagen are frequently used together in beauty and joint health supplements.
MSM supports collagen synthesis by providing sulfur needed for connective tissue formation.
Collagen provides direct structural protein peptides.
Comparison:
| MSM | Collagen |
|
Supports natural collagen production Small molecule compound Fully water-soluble Neutral taste |
Direct protein source Higher dosage required May affect beverage clarity Derived from animal sources |
Combination advantage:
MSM + Collagen formulations are widely used in:
- Beauty supplements
- Joint health drinks
- Skin elasticity products
- Sports recovery formulas
MSM vs Chondroitin
Chondroitin is another joint support ingredient often combined with MSM.
Chondroitin supports cartilage hydration and elasticity, while MSM supports collagen formation and anti-inflammatory activity.
Comparison:
| MSM | Chondroitin |
|
Sulfur source Anti-inflammatory support Collagen synthesis |
Cartilage hydration Joint cushioning Structural joint support |
Formulation trend:
MSM + Glucosamine + Chondroitin is one of the most popular joint support combinations in Europe and North America.
Bulk Supply of MSM Powder
We supply high-purity Methyl Sulfonyl Methane Powder with 99.9% specification, bulk B2B applications across the nutraceutical, pharmaceutical, and cosmetic industries.
| Standard MOQ: | Flexible MOQ available for: |
|
1 kg for sample orders 25 kg for commercial orders Bulk quantities available up to 20 tons |
R&D projects Pilot production New product development |
Packaging
| Standard packaging: | Custom packaging available: |
|
25kg fiber drum with PE inner liner 25kg kraft paper bag with inner liner 1000kg jumbo bag |
1kg foil bag 5kg aluminum bag 10kg bulk bag Private label packaging |
OEM Service
We provide OEM support for supplement brands and contract manufacturers.
OEM capabilities:
- Custom particle size
- Custom packaging
- Custom labeling
- Blending service
- Premix formulation
Private Label
| Private label services available for: | Services include: |
|
|
Lead Time
Sample lead time: 2–3 working days
Standard order lead time: 5–10 working days
Bulk production: 10–20 working days
Large contract orders: Scheduled production available
FAQ
Q: Does your MSM meet FDA GRAS and EU dietary supplement standards?
Yes, our MSM is classified as GRAS by the FDA and fully compliant with EU Regulation (EC) No. 1161/2011 for use in dietary supplements. We provide all necessary regulatory documentation for market access.
Q: Can you customize the particle size and packaging for our production needs?
Absolutely. We offer customizable particle sizes (20-120 mesh) and packaging options (1kg to 1000kg). Our team can tailor solutions to match your formulation and production line requirements.
Q: Is your MSM vegan, non-GMO, and allergen-free?
Yes, it is vegan-friendly (no animal-derived ingredients), Non-GMO Project Verified, and free from common allergens (soy, wheat, nuts, dairy, shellfish). We provide official certifications to confirm these attributes.
Q: What is the lead time for bulk orders, and do you offer sample testing?
Standard lead time is 7-12 working days for orders under 500kg, and 15-20 working days for large-scale orders (≥1000kg). Free 100g-500g samples are available for R&D testing, with results matching bulk production quality.
Q: How is your MSM produced, and what ensures its 99.9% purity?
Our MSM is produced via an advanced multi-stage distillation process, which eliminates contaminants more effectively than crystallization methods. Each batch undergoes third-party HPLC testing to confirm 99.9% purity.
Q: Can you provide documentation for EFSA/FDA product registration?
We supply comprehensive compliance documents, including COA, GRAS notification, toxicology data summary, and allergen declarations, to support your registration with EFSA, FDA, or local regulatory bodies.
Q: Is MSM compatible with other supplement ingredients like glucosamine or vitamin C?
Yes, it is chemically inert and compatible with most common supplement ingredients, including glucosamine, chondroitin, vitamin C, and herbal extracts. We can provide compatibility testing reports upon request.
Why Choose Us as Your Supplier?
Ultra-High Purity Commitment: 99.9% purity guaranteed, with third-party testing for every batch, exceeding industry standards .
Regulatory Expertise: Deep understanding of global regulations (FDA, EU, Canada) to ensure seamless market access for your products .
Customization Capabilities: Flexible particle size, packaging, and labeling options to meet your specific formulation and branding needs.
Stable Supply Chain: Annual production capacity of 20,000+ tons, ensuring on-time delivery even for large-volume, long-term contracts.
Technical Support: Dedicated B2B team provides formulation advice, compatibility testing, and regulatory guidance tailored to pharmaceutical and nutraceutical brands.
Competitive Pricing: Direct supply chain with no middlemen, offering cost advantages for bulk purchases without compromising quality.
Contact Us for a Quote or Sample
Ready to enhance your formulations with premium Methyl Sulfonyl Methane Powder 99.9%?
Our products are for commercial/industrial use only. Contact our B2B sales team to discuss your requirements, request a sample, or get a customized quotation.
Email: info@watersolu.com
Phone: +86 13484914978
WhatsApp: +86 17396654828
Website: www.watersolu.com
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